| 13.08.2021 (17:30): SØNDERJYSKE - FC MIDTJYLLAND | |
| | 4. | 0-1 | Junior Brumado | Morten Krogh | | | 88. | 0-2 | Victor Lind | | | |
| SØNDERJYSKE | FC MIDTJYLLAND | |
| | Lawrence Thomas | Jonas Lössl | | | Emil Holm | Dion Cools  (13) | | | Stefan Gartenmann  (60) | Erik Sviatchenko | | | Duplexe Tchamba | Paulinho | | | Marc Dal Hende | Joel Andersson (41) | | | Emil Kornvig (67) | Raphael Onyedika | | | Victor Ekani (75) | Evander Ferreira (78) | | | Mads Albæk (26) | Nikolas Dyhr | | | Rilwan Hassan (63) | Anders Dreyer (78) | | | Anders K. Jacobsen (75) | Junior Brumado  (4) | | | Isak Steiner Jensen (67) | Gustav Isaksen (65) | | |
| | | Philipp Schmiedl  (75) | Awer Mabil (65) | | | Julius Eskesen (63) | Elias Olafsson | | | Pierre Kanstrup | Mikael Anderson (78) | | | Kristofer Kristinsson (67) | Charles | | | Emil Frederiksen (75) | Nicolas Madsen (13) | | | Rasmus Vinderslev (67) | Mads Hansen | | | Nicolai Flø | Victor Lind (78) / (88) | | |
| 13.08.2021 (19:15): VIBORG - RANDERS FC | |
| | 25. | 0-1 | Mikkel Kallesøe | Aydin Uslu | | | 35. | 1-1 | Jakob Bonde | | | | 36. | 1-2 | Vito Hammershøy-Mistrati | | | |
| | Lucas Lund Pedersen | Patrik Carlgren | | | Daniel Anyembe (87) | Mikkel Kallesøe (35) | | | Lars Kramer (61) | Simon Piesinger | | | Mads Lauritsen | Erik Marxen (67) | | | Christian Sørensen (33) | Björn Kopplin | | | Justin Lonwijk (67) / (87) | Tobias Klysner (88) | | | Jeppe Grønning | Lasse Berg Johnsen | | | Jakob Bonde (35) | Frederik Lauenborg | | | Tobias Bech (75) | Simon Tibbling (73) | | | Sebastian Grønning (75) | Vito Hammershøy-Mistrati (36) / (84) | | | Younes Bakiz (67) | Marvin Egho (88) | | |
| | | Lorenzo Gordinho | Joel Kabongo (84) | | | Frans Putros (87) | Jakob Ankersen (73) | | | Jeff Mensah | Oliver Bundgaard (88) | | | Clint Leemans (75) | Issah Salou | | | Sofus Berger (87) | Jonas Dakir | | | Can Dursun | Filip Bundgaard | | | Ibrahim Said (75) | Nicolai Brock-Madsen (88) | | |
| 13.08.2021 (21:00): BRØNDBY - FC NORDSJÆLLAND | |
| | 49. | 0-1 | Kian Hansen | Peter Kjærsgaard | | |
| | Mads Hermansen | Peter Vindahl Jensen | | | Anton Skipper (75) | Mads Døhr Tychosen | | | Andreas Maxsø | Kian Hansen (49) | | | Kevin Tshiembe | Adamo Nagalo (73) | | | Andreas Bruus | Oliver Villadsen (90) | | | Morten Frendrup (89) | Magnus Kofod Andersen | | | Anis Ben Slimane | Leo Walta (74) | | | Kevin Mensah | Martin Frese (36) / (74) | | | Simon Hedlund | Mohamed Diomande (88) | | | Mikael Uhre (39) | Lasso Coulibaly (45) / (86) | | | Andrija Pavlovic (64) | Andreas Schjelderup (65) | | |
| | | Jens Martin Gammelby (89) | Maxwell Woledzi (73) | | | Rezan Corlu (64) | Jacob Christensen (74) | | | Oskar Fallenius | Simon Adingra (65) | | | Rasmus Wikström | Oliver Antman (86) | | | Andreas Pyndt | Ivan Mesik | | | Mathias Kvistgaarden (75) | Daniel Svensson (74) | | | Jonathan Ægidius | Andreas Gülstorff | | |
| 15.08.2021 (16:00): OB - SILKEBORG | |
| | 50. | 1-0 | Mart Lieder | Jonas Hansen | | | 82. | 1-1 | Nicklas Røjkjær | | | |
| | Oliver Christensen | Nicolai Larsen | | | Alexander Juel Andersen | Rasmus Carstensen | | | Jeppe Tverskov | Tobias Salquist | | | Kasper Larsen | André Calisir | | | Jørgen Skjelvik | Gustav Dahl (78) | | | Jens Jakob Thomasen (39) / (75) | Stefan Teitur Thordarson (66) / (73) | | | Issam Jebali | Mark Brink | | | Aron Elis Thrandarson (76) | Mads Kaalund (53) / (73) | | | Emmanuel Sabbi (76) | Sebastian Jørgensen | | | Bashkim Kadrii (89) | Nicolai Vallys | | | Mart Lieder (50) / (63) | Nicklas Helenius (78) | | |
| | | Hans Christian Bernat | Joel Felix | | | Max Fenger (63) | Pelle Mattsson | | | Tarik Ibrahimagic (75) | Alexander Lind (78) | | | Troels Kløve (76) | Stan van Bladeren | | | Robin Østrøm | Gustav Marcussen (73) | | | Moses Opondo (76) | Anders Klynge (73) | | | Mads Frøkjær-Jensen (89) | Nicklas Røjkjær (78) / (82) | | |
| 15.08.2021 (18:00): AGF - FC KØBENHAVN | |
| | 21. | 0-1 | Mohamed Daramy | Jacob A. Sundberg | | | 45. | 0-2 | Pep Biel | | | | 58. | 1-2 | Patrick Mortensen, straffe | | | | 59. | 1-3 | Pep Biel | | | |
| | Jesper Hansen | Kamil Grabara | | | Sebastian Hausner (67) | Kevin Diks | | | Yann Aurel Bisseck | David Khocholava (50) | | | Frederik Tingager | Nicolai Boilesen (57) | | | Anthony D'Alberto (60) | Victor Kristiansen | | | Nicolai Poulsen | Jens Stage (90) | | | Patrick Olsen (84) | Carlos Zeca | | | Eric Kahl (83) | Mohamed Daramy (21) / (81) | | | Dawid Kurminowski | Pep Biel (45,59) / (90) | | | Patrick Mortensen (58) / (84) | Rasmus Falk (90) | | | Albert Grønbæk (72) | Jonas Wind (85) / (87) | | |
| | | Gift Links (83) | Pierre Bengtsson (90) | | | Oliver Lund (60) | Lukas Lerager (81) | | | Jon Thorsteinsson (72) | Karl-Johan Johnsson | | | Thomas Kristensen | Peter Ankersen | | | Frederik Brandhof (84) | William Bøving | | | Daniel Gadegaard Andersen | Marios Oikonomou (90) | | | Alexander Ammitzbøll (84) | Rasmus Højlund (87) | | |
| 16.08.2021 (19:00): VEJLE - AAB | |
| | 33. | 0-1 | Iver Fossum | Jakob Kehlet | | |
| | Alexander Brunst | Jacob Rinne | | | Kevin Yamga (87) | Mathias Ross | | | Denis Kolinger | Rasmus Thelander | | | Manjrekar James | Daniel Granli | | | Viljormur Davidsen | Kristoffer Pallesen | | | Kevin Custovic (77) | Pedro Ferreira (48) | | | Saeid Ezatolahi (46) | Malthe Højholt (64) / (69) | | | Jacob Schoop (46) | Frederik Børsting (60) | | | Allan Sousa | Iver Fossum (33) | | | Wahid Faghir (88) | Milan Makaric (81) | | | Dimitrios Emmanouilidis (46) | Louka Prip (81) | | |
| | | Juhani Ojala | Jakob Ahlmann (60) | | | Lukas Engel (46) | Tim Prica (81) | | | Arbnor Mucolli (46) | Anders Hagelskjær | | | Aleksei Chernov | Magnus Christensen (81) | | | Brandon Pierrick (87) | Andreas Hansen | | | Hans Høllsberg (46) | Casper Gedsted | | | Lundrim Hetemi (77) | Marcus Hannesbo (69) | | |
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