| 17.09.2021 (19:00): AAB - OB | |
| | 70. | 1-0 | Rasmus Thelander | Jens Maae | | | 84. | 2-0 | Anders Hagelskjær | | | |
| | Jacob Rinne | Hans Christian Bernat | | | Mathias Ross  (60) /  (61) | Nicholas Mickelson (86) | | | Rasmus Thelander  (70) / (90) | Kasper Larsen (90) | | | Daniel Granli | Jeppe Tverskov (87) | | | Kristoffer Pallesen | Jørgen Skjelvik | | | Malthe Højholt (85) | Jens Jakob Thomasen (77) | | | Pedro Ferreira (90) | Aron Elis Thrandarson (27) | | | Frederik Børsting (65) / (74) | Emmanuel Sabbi (86) | | | Iver Fossum | Mads Frøkjær-Jensen (77) | | | Louka Prip (61) | Troels Kløve | | | Milan Makaric (85) | Bashkim Kadrii (77) | | |
| | | Jakob Ahlmann  (74) / (90) | Alexander Juel Andersen (86) | | | Aleksandar Trajkovski (61) | Mart Lieder (77) | | | Tim Prica (85) | Max Fenger (77) | | | Anders Hagelskjær (61) / (74) / (84) | Ayo Okosun (86) | | | Magnus Christensen (85) | Robin Østrøm | | | Andreas Hansen | Moses Opondo (77) | | | Marcus Hannesbo | Sayouba Mandé | | |
| 19.09.2021 (14:00): VEJLE - VIBORG | |
| | 14. | 0-1 | Sebastian Grønning | Aydin Uslu | | | 36. | 1-1 | Luka Djordjevic | | | |
| | Sten Grytebust | Lucas Lund Pedersen | | | Tobias Mølgaard (64) | Frans Putros | | | Manjrekar James | Lars Kramer (85) | | | Jerome Opoku | Mads Lauritsen | | | Viljormur Davidsen (64) | Christian Sørensen | | | Allan Sousa | Justin Lonwijk (75) | | | Mouhamadou Drammeh | Jeppe Grønning | | | Hans Høllsberg | Jakob Bonde | | | Arbnor Mucolli (51) / (86) | Ibrahim Said (60) | | | Andrés Ponce (73) | Sebastian Grønning (14) | | | Luka Djordjevic (36) / (46) | Jay-Roy Grot (60) | | |
| | | Alexander Brunst | Lorenzo Gordinho | | | Heron (64) | Alassana Jatta (60) | | | Saeid Ezatolahi | Clint Leemans (75) | | | Lukas Engel (73) | Mikkel Andersen | | | Kevin Custovic (64) | Sofus Berger | | | Dimitrios Emmanoulidis (46) | Tobias Bech (60) | | | Lundrim Hetemi (86) | Frederik Christensen | | |
| 19.09.2021 (14:00): RANDERS FC - FC NORDSJÆLLAND | |
| | 8. | 1-0 | Stephen Odey | Jakob A. Sundberg | | | 9. | 1-1 | Martin Frese | | | | 24. | 2-1 | Alhaji Kamara | | | | 34. | 3-1 | Stephen Odey | | | | 44. | 3-2 | Simon Adingra | | | |
| RANDERS FC | FC NORDSJÆLLAND | |
| | Patrik Carlgren | Eduardo dos Santos Haesler | | | Mikkel Kallesøe | Mads Døhr Tychosen (82) | | | Simon Graves | Kian Hansen | | | Erik Marxen | Adamo Nagalo | | | Oliver Bundgaard | Oliver Villadsen (46) | | | Tobias Klysner (88) | Abu Francis (40) / (46) | | | Lasse Berg Johnsen | Magnus Kofod Andersen (27) / (86) | | | Frederik Lauenborg (74) | Martin Frese (9) | | | Simon Tibbling (54) / (64) | Simon Adingra (44) / (72) | | | Stephen Odey (8,34) / (87) | Lasso Coulibaly | | | Alhaji Kamara (24) / (74) | Andreas Schjelderup | | |
| | | Simon Piesinger (88) | Maxwell Woledzi (86) | | | Tosin Kehinde (64) | Jacob Christensen | | | Jesper Lauridsen | Ibrahim Sadiq (72) | | | Vito Hammershøy-Mistrati (74) | Emmanuel Ogura | | | Mathias Greve | Oliver Antman (46) | | | Vincent Onovo (74) | Daniel Svensson (82) | | | Nicolai Brock-Madsen (87) | Leo Walta (46) | | |
| 19.09.2021 (16:00): SØNDERJYSKE - BRØNDBY | |
| | 90. | 1-0 | Abdulrahman Taiwo | Morten Krogh | | |
| | Lawrence Thomas | Mads Hermansen | | | Emil Holm (90) | Sigurd Rosted (90) | | | Stefan Gartenmann | Andreas Maxsø (66) | | | Søren Reese | Kevin Tshiembe (34) / (46) | | | Marc Dal Hende | Jens Martin Gammelby (80) | | | Emil Kornvig | Anis Ben Slimane (90) | | | Victor Ekani (82) | Josip Radosevic | | | Mads Albæk | Mathias Greve (38) / (77) | | | Julius Eskesen (64) | Kevin Mensah | | | Abdulrahman Taiwo (7) / (90) / (90) | Mikael Uhre (64) | | | Daniel Prosser (64) | Simon Hedlund (65) | | |
| | | Maxime Soulas | Andrija Pavlovic (64) | | | Kristofer Kristinsson (90) | Thomas Mikkelsen | | | Jeppe Simonsen (64) | Andreas Bruus (80) | | | Rasmus Vinderslev (82) | Morten Frendrup | | | Nicolai Flø | Christian Cappis (77) | | | Isak Steiner Jensen (64) | Marko Divkovic (65) | | | Rilwan Hassan | Tobias Børkeeiet ((46) | | |
| 19.09.2021 (18:00): FC KØBENHAVN - FC MIDTJYLLAND | |
| | 47. | 0-1 | Junior Brumado | Jakob Kehlet | | |
| FC KØBENHAVN | FC MIDTJYLLAND | |
| | Kamil Grabara | Elias Olafsson (90) | | | Kevin Diks | Henrik Dalsgaard | | | David Khocholava (84) / (88) | Erik Sviatchenko | | | Nicolai Boilesen (13) | Juninho | | | Victor Kristiansen | Joel Andersson (88) | | | Carlos Zeca | Raphael Onyedika | | | Lukas Lerager (68) | Evander Ferreira  (27) | | | Jens Stage (61) / (68) | Paulinho | | | Pep Biel | Gustav Isaksen (81) | | | William Bøving (55) | Junior Brumado (47) / (88) | | | Jonas Wind | Pione Sisto (33) | | |
| | | Victor Nelsson | Dion Cools (88) | | | Isak Bergmann Johannesson (68) | Daniel Høegh | | | Kamil Wilczek (55) | Jared Thompson | | | Andri Fannar Baldursson | Charles (33) | | | Karl-Johan Johnsson | Nikolas Dyhr | | | Peter Ankersen (68) | Mads Hansen (88) | | | Rasmus Højlund (88) | Victor Lind (81) | | |
| 20.09.2021 (19:00): SILKEBORG - AGF | |
| | 71. | 0-1 | Yann Aurel Bisseck | Jørgen Daugbjerg Burchardt | | | 73. | 0-2 | Mikael Anderson | | | |
| | Nicolai Larsen | Jesper Hansen | | | Rasmus Carstensen | Oliver Lund | | | Tobias Salquist | Sebastian Hausner | | | André Calisir | Yann Aurel Bisseck (71) | | | Gustav Dahl | Eric Kahl | | | Stefan Teitur Thordarson (40) / (74) | Albert Grønbæk (81) | | | Mark Brink | Nicolai Poulsen | | | Andreas Oggesen (67) | Mikael Anderson (73) / (79) / (88) | | | Anders Klynge (46) | Mustapha Bundu (57) | | | Nicolai Vallys (90) | Patrick Mortensen (36) / (88) | | | Nicklas Helenius | Jon Thorsteinsson (61) | | |
| | | Joel Felix | Frederik Tingager | | | Oliver Sonne | Patrick Olsen (81) | | | Pelle Mattsson | Jesper Juelsgård | | | Søren Tengstedt (74) | Dawid Kurminowski (88) | | | Stan van Bladeren | Anthony D'Alberto (88) | | | Robert Gojani (67) | Frederik Brandhof ( | | | Sebastian Jørgensen (46) | Daniel Gadegaard Andersen | | |
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