| 20.03.2022 (14:30): SILKEBORG - FC MIDTJYLLAND | |
| | 90. | 0-1 | Henrik Dalsgaard | Sandi Putros | | |
| Nicolai Larsen | Elias Olafsson  (85) | | | Rasmus Carstensen  (74) | Henrik Dalsgaard  (90) | | | Tobias Salquist | Daniel Høegh | | | André Calisir | Mads Døhr Thychosen | | | Lukas Engel (39) | Joel Andersson | | | Anders Klynge | Raphael Onyedika | | | Mark Brink (80) | Evander Ferreira | | | Robert Gojani | Nikolas Dyhr (75) | | | Sebastian Jørgensen | Gustav Isaksen (46) | | | Stefan Teitur Thordarson (58) / (63) | Junior Brumado (72) | | | Nicklas Helenius | Marrony (46) | | |
| | | Oliver Sonne  (39) | Pione Sisto (46) | | | Pelle Mattsson (80) | Max Meier | | | Nicolai Vallys (63) / (90) | Edward Chilufya (46) | | | Søren Tengstedt | Vagner Love (72) | | | Stan van Bladeren | Paulinho (75) | | | Alexander Busch | David Ousted (85) | | | Frederik Carstensen | Charles | | |
| 20.03.2022 (14:30): SØNDERJYSKE - RANDERS FC | |
| | 60. | 1-0 | Stefan Gartenmann | Mikkel Redder | | | 64. | 1-1 | Stephen Odey, straffe | | | |
| Lawrence Thomas | Patrik Carlgren | | | Maxime Soulas | Björn Kopplin (20) | | | Stefan Gartenmann (60) / (80) | Simon Piesinger | | | Duplexe Tchamba | Simon Graves (35) | | | Emil Holm (38) / (73) | Oliver Bundgaard | | | Mads Albæk | Lasse Berg Johnsen | | | Nikolaj Thomsen (69) | Frederik Lauenborg | | | Marc Dal Hende | Tosin Kehinde (90) | | | Emil Frederiksen (69) | Vito Hammershøy-Mistrati (82) | | | Peter Christiansen (82) | Jakob Ankersen (71) | | | Emil Kornvig | Stephen Odey (64) | | |
| | | Julius Eskesen (69) | Hugo Andersson | | | Bubacarr Sanneh | Simon Tibbling | | | Kristofer Kristinsson (73) | Jesper Lauridsen | | | Atli Barkarson | Tobias Klysner (71) | | | Rasmus Vinderslev (69) | Jonas Dakir | | | Nicolai Flø | Filip Bundgaard (90) | | | Isak Jensen (82) | Nicolai Brock-Madsen (82) | | |
| 20.03.2022 (14:30): VEJLE - OB | |
| | 5. | 1-0 | Abnor Mucolli | Morten Krogh | | | 41. | 2-0 | Miiko Albornoz | | | |
| Alexander Brunst | Hans Christian Bernat | | | Denis Kolinger | Nicholas Mickelson | | | Raul Albertosa | Jeppe Tverskov (40) | | | Jerome Opoku | Mihajlo Ivancevic (40) | | | Tobias Mølgaard | Joel King (46) | | | Arbnor Mucolli (5) / (84) | Jens Jakob Thomasen | | | Lundrim Hetemi (9) | Ayo Okosun | | | Mouhamadou Drammeh | Emmanuel Sabbi (70) | | | Miiko Albernoz (41) / (70) | Issam Jebali (70) | | | Allan Sousa (70) | Sander Svendsen (46) | | | Andrés Ponce (4) / (57) | Max Fenger (89) | | |
| | | Thomas Gundelund (70) | Alexander Juel Andersen | | | Kevin Custovic | Jakob Breum (89) | | | Dimitrios Emmanoulidis (84) | Bashkim Kadrii (70) | | | Luka Djordjevic (57) | Jørgen Skjelvik (46) | | | Edgar Babyan (70) | Aron Elis Thrandarson (46) | | | Lucas Hägg | Mads Frøkjær-Jensen (70) / (90) | | | Oliver Provstgaard | Sayouba Mandé | | |
| 20.03.2022 (14:30): AAB - BRØNDBY | |
| | 33. | 1-0 | Louka Prip, straffe | Jens Maae | | | 61. | 2-0 | Louka Prip, straffe | | | | 69. | 3-0 | Milan Makaric | | | |
| Jacob Rinne | Mads Hermansen | | | Mathias Ross | Henrik Heggheim  (59) | | | Daniel Granli (90) | Andreas Maxsø | | | Anders Hagelskjær | Sigurd Rosted | | | Kristoffer Pallesen (87) | Andreas Bruus | | | Magnus Christensen | Josip Radosevic | | | Iver Fossum | Joe Bell (57) | | | Jakob Ahlmann (68) | Blas Riveros | | | Kasper Kusk (78) | Anis Ben Slimane (67) / (88) | | | Louka Prip (33,61) / (87) | Mathias Greve (57) | | | Milan Makaric (69) / (78) | Marko Divkovic (75) | | |
| | | Anosike Ementa (87) | Carl Björk (57) / (81) | | | Vladimir Prijovic | Thomas Mikkelsen | | | Anders Noshe (87) | Kevin Tshiembe | | | Casper Gedsted (68) | Frederik Ibsen (75) | | | Oliver Ross (78) | Oskar Fallenius | | | Kasper Høgh (78) | Christian Cappis (88) | | | Theo Sander | Mathias Kvistgaarden (57) | | |
| 20.03.2022 (14:30): FC KØBENHAVN - FC NORDSJÆLLAND | |
| | 7. | 1-0 | Akinkunmi Amoo | Mads-Kristoffer Kristoffersen | | |
| FC KØBENHAVN | FC NORDSJÆLLAND | |
| Kamil Grabara | Andreas Hansen | | | Elias Jelert (86) | Oliver Villadsen | | | Denis Vavro | Adamo Nagalo (78) | | | Nicolai Boilesen | Erik Marxen | | | Kevin Diks (81) | Daniel Svensson (72) | | | Rasmus Falk | Magnus Kofod Andersen | | | Jens Stage (31) | Mads Bidstrup (78) | | | Akinkunmi Amoo (7) / (60) | Mads Kristian Hansen | | | Pep Biel (86) | Mohamed Diomande (72) | | | Paul Mukairu (46) | Oliver Antman | | | Khouma Babacar (60) | Benjamin Nygren (67) | | |
| | | David Khocholava | Maxwell Woledzi (78) | | | Isak Bergmann Johannesson (86) | Martin Frese (72) | | | Nicolai Jørgensen (60) | Jacob Christensen (72) | | | Karl-Johan Johnsson | Abu Francis | | | Peter Ankersen (86) | Emmanuel Ogura | | | William Bøving (46) | Simon Adingra (67) | | | Roony Bardaghji (60) | Lasso Coulibaly (78) | | |
| 20.03.2022 (14:30): AGF - VIBORG | |
| | 16. | 1-0 | Mikael Anderson | Peter Kjærsgaard | | | 59. | 1-1 | Nicolas Bürgy | | | |
| Jesper Hansen | Lucas Lund Pedersen | | | Alexander Munksgaard (19) | Daniel Anyembe (51) / (73) | | | Yann Aurel Bisseck | Nicolas Bürgy (59) | | | Sebastian Hausner (79) /  (90) | Mads Lauritsen | | | Eric Kahl (88) | Christian Sørensen | | | Nicolai Poulsen (89) | Jakob Bonde (60) | | | Albert Grønbæk (34) / (64) | Jeppe Grønning | | | Jack Wilshere (90) | Justin Lonwijk | | | Mikael Anderson (16) / (90) | Younes Bakiz | | | Frederik Brandhof (50) / (85) | Alassana Jatta (60) | | | Dawid Kurminowski (64) | Tobias Bech (85) | | |
| | | Frederik Tingager | Frans Putros (73) / (85) | | | Mustapha Bundu (64) | Lars Kramer | | | Patrick Mortensen (64) | Marokhy Ndione (60) | | | Oliver Lund | Clint Leemans (60) / (90) | | | Daniel Gadegaard Andersen | Jan Zamburek (85) | | | Frederik Ihler (85) | Kasper Kiilerich | | | Anthony D'Alberto (19) / (27) | Mads Søndergaard | | |
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