| 10.09.2021 (18:00): FC MIDTJYLLAND - FC NORDSJÆLLAND | |
| | 47. | 1-0 | Gustav Isaksen | Mikkel Redder | | | 77. | 2-0 | Victor Lind | | | |
| FC MIDTJYLLAND | FC NORDSJÆLLAND | |
| | Elias Olafsson | Eduardo dos Santos Haesler | | | Henrik Dalsgaard | Mads Døhr Tychosen | | | Erik Sviatchenko  (89) | Kian Hansen  (79) | | | Juninho | Adamo Nagalo | | | Joel Andersson | Simon Adingra | | | Raphael Onyedika | Abu Francis (87) | | | Evander Ferreira | Magnus Kofod Andersen (69) | | | Nikolas Dyhr (63) | Martin Frese (69) | | | Gustav Isaksen  (47) / (72) | Mohamed Diomande (15) / (79) | | | Junior Brumado (63) | Lasso Coulibaly | | | Pione Sisto (85) | Andreas Schjelderup (79) | | |
| | | Dion Cools  (63) | Maxwell Woledzi (79) | | | Awer Mabil (85) | Jacob Christensen (69) | | | Oliver Sørensen | Oliver Antman (79) | | | Jared Thompson | Oliver Villadsen (69) | | | Charles | Daniel Svensson (79) | | | Jens-Lys Cajuste (63) | Andreas Gülstorff | | | Victor Lind (72) / (77) | Leo Walta | | |
| 10.09.2021 (20:00): BRØNDBY - SILKEBORG | |
| | 20. | 0-1 | Mark Brink | Mads-Kristoffer Kristoffersen | | | 39. | 1-1 | Simon Hedlund | | | |
| | Mads Hermansen | Nicolai Larsen | | | Andreas Bruus (73) | Rasmus Carstensen | | | Andreas Maxsø | Tobias Salquist (27) | | | Kevin Tshiembe | Joel Felix (90) | | | Kevin Mensah | Gustav Dahl | | | Christian Cappis (73) | Stefan Teitur Thordarson | | | Josip Radosevic | Mark Brink (20) | | | Morten Frendrup (89) | Anders Klynge (77) | | | Mathias Greve (62) | Andreas Oggesen (65) | | | Mikael Uhre (73) | Nicolai Vallys | | | Simon Hedlund (39) / (86) | Nicklas Helenius (65) | | |
| | | Jens Martin Gammelby (73) | Oliver Sonne | | | Sigurd Rosted | Pelle Mattsson (90) | | | Andrija Pavlovic (73) | Søren Tengstedt (65) | | | Thomas Mikkelsen | Stan van Bladeren | | | Oskar Fallenius (73) | Gustav Marcussen | | | Anis Ben Slimane (62) | Robert Gojani (65) | | | Tobias Børkeeiet (86) | Sebastian Jørgensen (77) | | |
| 12.09.2021 (14:00): VIBORG - AAB | |
| | 10. | 1-0 | Mads Lauritsen | Peter Kjærsgaard | | | 44. | 1-1 | Pedro Ferreira | | | | 53. | 1-2 | Pedro Ferreira | | | | 84. | 2-2 | Sebastian Grønning | | | | 86. | 2-3 | Kasper Kusk | | | |
| | Lucas Lund Pedersen | Jacob Rinne | | | Daniel Anyembe | Mathias Ross (77) | | | Lars Kramer | Rasmus Thelander | | | Mads Lauritsen (10) / (52) | Daniel Granli | | | Christian Sørensen | Kristoffer Pallesen | | | Justin Lonwijk | Malthe Højholt (85) | | | Jeppe Grønning (31) / (85) | Pedro Ferreira (44,53) | | | Jakob Bonde (64) | Jakob Ahlmann (61) | | | Tobias Bech (77) | Iver Fossum | | | Sebastian Grønning (84) / (85) | Louka Prip | | | Jay-Roy Grot (77) | Milan Makaric (61) / (77) | | |
| | | Frans Putros (85) | Aleksandar Trajkovski (77) | | | Clint Leemans (85) | Anders Hagelskjær (77) | | | Mads Aaquist | Magnus Christensen | | | Mikkel Andersen | Kasper Kusk (85) / (86) | | | Kelian van der Kaap (52) | Andreas Hansen | | | Sofus Berger (77) | Frederik Børsting (61) | | | Ibrahim Said (77) | Marcus Hannesbo | | |
| 12.09.2021 (16:00): RANDERS FC - FC KØBENHAVN | |
| | 13. | 0-1 | William Bøving | Sandi Putros | | | 46. | 0-2 | Jens Stage | | | |
| | Patrik Carlgren | Kamil Grabara | | | Björn Kopplin | Kevin Diks | | | Simon Piesinger | David Khocholava | | | Erik Marxen (71) | Nicolai Boilesen | | | Oliver Bundgaard (80) | Victor Kristiansen | | | Tosin Kehinde | Carlos Zeca | | | Lasse Berg Johnsen | Lukas Lerager (74) | | | Frederik Lauenborg (58) | Jens Stage (46) / (82) | | | Simon Tibbling (58) | Pep Biel (90) | | | Vito Hammershøy-Mistrati (71) | William Bøving (12) / (67) | | | Alhaji Kamara | Jonas Wind (82) | | |
| | | Simon Graves (71) | Pierre Bengtsson | | | Jakob Ankersen (58) | Isak Bergmann Johannesson (67) | | | Jesper Lauridsen (80) / (81) | Kamil Wilczek (90) | | | Tobias Klysner | Andri Fannar Baldursson (82) | | | Jonas Dakir | Karl-Johan Johnsson | | | Vincent Onovo (71) | Peter Ankersen | | | Stephen Odey (58) | Rasmus Højlund (82) | | |
| 12.09.2021 (18:00): AGF - VEJLE | |
| | 60. | 1-0 | Mikael Anderson | Michael Tykgaard | | |
| | Jesper Hansen | Sten Grytebust | | | Frederik Tingager (46) | Tobias Mølgaard (78) | | | Yann Aurel Bisseck | Denis Kolinger (19) | | | Sebastian Hausner | Manjrekar James | | | Oliver Lund | Viljormur Davidsen (71) | | | Albert Grønbæk (85) | Allan Sousa | | | Patrick Olsen | Hans Høllsberg (58) | | | Frederik Brandhof (46) | Mouhamadou Drammeh (78) | | | Eric Kahl (85) | Arbnor Mucolli (86) | | | Patrick Mortensen | Dimitrios Emmanoulidis (62) | | | Jon Thorsteinsson | Luka Djordjevic (62) | | |
| | | Mustapha Bundu (46) | Alexander Brunst | | | Mikael Anderson (46) / (60) | Heron (71) | | | Alexander Munksgaard | Jerome Opoku | | | Jesper Juelsgård (85) | Saeid Ezatolahi (78) | | | Dawid Kurminowski | Lukas Engel (62) | | | Anthony D'Alberto (85) | Andrés Ponce (62) | | | Daniel Gadegaard Andersen | Kevin Custovic (78) | | |
| 13.09.2021 (19:00): OB - SØNDERJYSKE | |
| | 30. | 1-0 | Jørgen Skjelvik | Anders Poulsen | | | 39. | 2-0 | Mads Frøkjær-Jensen | | | | 44. | 2-1 | Daniel Prosser | | | |
| | Hans Christian Bernat (90) | Lawrence Thomas | | | Nicholas Mickelson (67) | Emil Holm (71) | | | Kasper Larsen | Stefan Gartenmann | | | Jeppe Tverskov | Søren Reese | | | Jørgen Skjelvik (30) | Marc Dal Hende | | | Aron Elis Thrandarson | Emil Kornvig (17) / (60) | | | Jens Jakob Thomasen (67) | Victor Ekani (61) / (73) | | | Emmanuel Sabbi | Mads Albæk | | | Mads Frøkjær-Jensen (39) / (83) | Rilwan Hassan (46) | | | Moses Opondo (83) | Andulrahman Taiwo | | | Bashkim Kadrii (90) | Daniel Prosser (44) / (81) | | |
| | | Alexander Juel Andersen (67) | Julius Eskesen (60) | | | Mart Lieder (83) | Maxime Soulas | | | Max Fenger (83) | Kristofer Kristinsson (81) | | | Ayo Okosun (90) | Jeppe Simonsen | | | Troels Kløve (67) | Rasmus Vinderslev (73) | | | Robin Østrøm | Nicolai Flø | | | Sayouba Mandé | Isak Steiner Jensen (46) | | |
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