| 18.04.2022 (16:00): FC KØBENHAVN - BRØNDBY | |
| | 52. | 1-0 | Pep Biel | Sandi Putros | | | 86. | 2-0 | Pep Biel | | | |
| | Kamil Grabara | Mads Hermansen | | | Peter Ankersen | Andreas Bruus  (87) | | | Denis Vavro | Sigurd Rosted  (89) | | | David Khocholava | Andreas Maxsø | | | Kevin Diks | Blas Riveros | | | Rasmus Falk (83) | Joe Bell | | | Lukas Lerager | Anis Ben Slimane | | | Roony Bardaghji (63) | Christian Cappis (69) | | | Pep Biel  (52,86) / (90) | Simon Hedlund (79) | | | Victor Claesson (72) | Mathias Kvistgaarden (69) | | | Khouma Babacar (72) | Marko Divkovic (28) | | |
| | | Nicolai Jørgensen  (72) / (89) | Henrik Heggheim | | | Paul Mukairu (63) | Mathias Greve (69) | | | Nicolai Boilesen | Carl Björk (69) | | | Karl-Johan Johnsson | Thomas Mikkelsen | | | William Bøving (72) | Kevin Tshiembe | | | Hakon Arnar Haraldsson (90) | Jagvir Singh Sidhu (79) / (82) | | | Elias Jelert | Christian Friedrich (87) | | |
| 18.04.2022 (18:00): FC MIDTJYLLAND - AAB | |
| | 38. | 1-0 | Evander Ferreira, straffe | Jørgen Daugbjerg Burchardt | | | 42. | 2-0 | Anders Dreyer | | | |
| | David Ousted | Jacob Rinne | | | Henrik Dalsgaard | Mathias Ross (37) /  (59) | | | Daniel Høegh | Rasmus Thelander | | | Mads Døhr Thychosen (84) | Anders Hagelskjær | | | Joel Andersson | Kristoffer Pallesen | | | Raphael Onyedika (90) | Malthe Højholt (77) | | | Evander Ferreira (38) / (79) | Iver Fossum | | | Paulinho (79) | Daniel Granli (77) | | | Gustav Isaksen (84) | Kasper Kusk (17) | | | Anders Dreyer (42) | Kasper Høgh (46) | | | Edward Chilufya (65) | Louka Prip (66) | | |
| | | Vagner Love (84) | Jakob Ahlmann (66) | | | Jared Thompson | Milan Makaric (46) | | | Charles (79) | Lucas Andersen (17) | | | Marrony | Anosike Ementa (77) | | | Nikolas Dyhr (79) | Casper Gedsted | | | Juninho (84) | Oliver Ross (77) | | | Junior Brumado (65) | Theo Sander | | | |
| 19.04.2022 (19:00): RANDERS FC - SILKEBORG | |
| | 26. | 1-0 | Vito Hammershøy-Mistrati | Michael Tykgaard | | | 40. | 1-1 | Nicklas Helenius | | | | 43. | 1-2 | Nicklas Helenius | | | |
| | Patrik Carlgren | Nicolai Larsen | | | Björn Kopplin (51) | Rasmus Carstensen | | | Simon Piesinger | Tobias Salquist | | | Simon Graves (75) | Joel Felix | | | Oliver Bundgaard (75) | Lukas Engel (90) | | | Jakob Ankersen (63) | Stefan Teitur Thordarson (46) | | | Frederik Lauenborg (75) | Mark Brink | | | Lasse Berg Johnsen (90) | Anders Klynge (85) | | | Tosin Kehinde | Sebastian Jørgensen (85) | | | Vito Hammershøy-Mistrati (26) | Nicolai Vallys | | | Stephen Odey | Nicklas Helenius (40,43) | | |
| | | Hugo Andersson (75) | Oliver Sonne (90) | | | Simon Tibbling (75) / (79) | Pelle Mattsson | | | Mads Enggård | Søren Tengstedt (85) | | | Jesper Lauridsen (90) | Stan van Bladeren | | | Tobias Klysner (75) | Robert Gojani (46) | | | Alexander Nybo | Andreas Oggesen (85) | | | Filip Bundgaard (63) | Alexander Busch | | | |
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