|   Esbjerg til 2. runde | |
| | 13.09.1978 | Start - Esbjerg 0-0 | | | | 27.09.1978 | Esbjerg - Start 1-0 | |
|  PS Kuopio til 2. runde | |
| | 13.09.1978 | PS Kuopio - B1903 2-1 | | | | 27.09.1978 | B1903 - PS Kuopio 4-4 | |
|   Dukla Prag til 2. runde | |
| | 13.09.1978 | Dukla Prag - Vicenza 1-0 | | | | 27.09.1978 | Vicenza - Dukla Prag 1-1 | |
| Milan til 2. runde | |
| | 13.09.1978 | Milan - Lokomotiva Kosice 1-0 | | | | 27.09.1978 | Lokomotiva Kosice - Milan 1-0 | |
|   Valencia til 2. runde | |
| | 13.09.1978 | CSKA Sofia - Valencia 2-1 | | | | 27.09.1978 | Valencia - CSKA Sofia 4-1 | |
|   Mönchengladbach til 2. runde | |
| | 13.09.1978 | Mönchengladbach - Sturm Graz 5-1 | | | | 27.09.1978 | Sturm Graz - Mönchengladbach 1-2 | |
|   Arges Pitesti til 2. runde | |
| | 13.09.1978 | Arges Pitesti - Panathinaikos 3-0 | | | | 27.09.1978 | Panathinaikos - Arges Pitesti 1-2 | |
|  Ajax til 2. runde | |
| | 13.09.1978 | Athletic Bilbao - Ajax 2-0 | | | | 27.09.1978 | Ajax - Athletic Bilbao 3-0 | |
|   Everton til 2. runde | |
| | 12.09.1978 | Finn Harps - Everton 0-5 | | | | 26.09.1978 | Everton - Finn Harps 5-0 | |
|   Lausanne Sports til 2. runde | |
| | 13.09.1978 | Jeunesse d'Esch - Lausanne Sports 0-0 | | | | 26.09.1978 | Lausanne Sports - Jeunesse d'Esch 2-0 | |
|   Benfica til 2. runde | |
| | 13.09.1978 | Nantes - Benfica 0-2 | | | | 27.09.1978 | Benfica - Nantes 0-0 | |
| Sporting Gijon til 2. runde | |
| | 13.09.1978 | Sporting Gijon - Torino 3-0 | | | | 27.09.1978 | Torino - Sporting Gijon 1-0 | |
|  Sporting Braga til 2. runde | |
| | 13.09.1978 | Sporting Braga - Hibernians 5-0 | | | | 20.09.1978 | Hibernians - Sporting Braga 3-2 | |
|  West Bromwich til 2. runde | |
| | 13.09.1978 | Galatasaray - West Bromwich 1-3 | | | | 27.09.1978 | West Bromwich - Galatasaray 3-1 | |
|   Røde Stjerne Beograd til 2. runde | |
| | 13.09.1978 | Dynamo Berlin - Røde Stjerne Beograd 5-2 | | | | 26.09.1978 | Røde Stjerne Beograd - Dynamo Berlin 4-1 | |
| Stuttgart til 2. runde | |
| | 13.09.1978 | FC Basel - Stuttgart 2-3 | | | | 27.09.1978 | Stuttgart - FC Basel 4-1 | |
|  Torpedo Moskva til 2. runde | |
| | 13.09.1978 | Torpedo Moskva - Molde 4-0 | | | | 27.09.1978 | Molde - Torpedo Moskva 3-3 | |
|  RC Strasbourg til 2. runde | |
| | 13.09.1978 | Elfsborg - RC Strasbourg 2-0 | | | | 27.09.1978 | RC Strasbourg - Elfsborg 4-1 | |
|  Duisburg til 2. runde | |
| | 13.09.1978 | Duisburg - Lech Poznan 5-0 | | | | 27.09.1978 | Lech Poznan - Duisburg 2-5 | |
|   Standard Liége til 2. runde | |
| | 12.09.1978 | Standard Liège - Dundee United 1-0 | | | | 27.09.1978 | Dundee United - Standard Liège 0-0 | |
| Arsenal til 2. runde | |
| | 13.09.1978 | Arsenal - Lokomotive Leipzig 3-0 | | | | 27.09.1978 | Lokomotive Leipzig - Arsenal 1-4 | |
| Carl Zeiss Jena til 2. runde | |
| | 13.09.1978 | Carl Zeiss Jena - Lierse 1-0 | | | | 27.09.1978 | Lierse - Carl Zeiss Jena 2-2 | |
|   Vestmannaøerne til 2. runde | |
| | 05.09.1978 | Vestmannaøerne - Glentoran 0-0 | | | | 14.09.1978 | Glentoran - Vestmannaøerne 1-1 | |
| Manchester City til 2. runde | |
| | 13.09.1978 | Twente - Manchester City 1-1 | | | | 27.09.1978 | Manchester City - Twente 3-2 | |
| Hibernian til 2. runde | |
| | 13.09.1978 | Hibernian - IFK Norrköping 3-2 | | | | 27.09.1978 | IFK Norrköping - Hibernian 0-0 | |
|  Poli Timisoara til 2. runde | |
| | 13.09.1978 | Poli Timisoara - MTK Budapest 2-0 | | | | 27.09.1978 | MTK Budapest - Poli Timisoara 2-1 | |
|  Slask Wrochlaw til 2. runde | |
| | 16.09.1978 | Pezoporikos - Slask Wroclaw 2-2 | | | | 27.09.1978 | Slask Wroclaw - Pezoporikos 5-1 | |
| Levski-Spartak Sofia til 2. runde | |
| | 14.09.1978 | Olympiakos Piræus - Levski-Spartak Sofia 2-1 | | | | 28.09.1978 | Levski-Spartak Sofia - Olympiakos Piræus 3-1 | |
| Dinamo Tbilisi til 2. runde | |
| | 13.09.1978 | Dinamo Tbilisi - Napoli 2-0 | | | | 27.09.1978 | Napoli - Dinamo Tbilisi 1-1 | |
| Hajduk Split til 2. runde | |
| | 13.09.1978 | Hajduk Split - Rapid Wien 2-0 | | | | 27.09.1978 | Rapid Wien - Hajduk Split 2-1 | |
| Hertha Berlin til 2. runde | |
| | 13.09.1978 | Hertha Berlin - Trakia Plovdiv 0-0 | | | | 27.09.1978 | Trakia Plovdiv - Hertha Berlin 1-2 | |
| Honved Budapest til 2. runde | |
| | 14.09.1978 | Honved Budapest - Adanaspor 6-0 | | | | 27.09.1978 | Adanaspor - Honved Budapest 2-2 | |
|
|
Forside