|  FC Pafos til 1/8 finaler | |
| | 13.02.2025 | Omonia Nicosia - FC Pafos 1-1 | | 20.02.2025 | FC Pafos - Omonia Nicosia 2-1 |
| 51. | 1-0 | Willy Semedo | | 28. | 1-0 | Bruno |
| 84. | 1-1 | Mislav Orsic | | 60. | 1-1 | Stevan Jovetic |
| | | | | 65. | 2-1 | Jonathan Silva |
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|   Molde til 1/8 finaler (vandt 5-4 på straffe) | |
| | 13.02.2025 | Molde - Shamrock Rovers 0-1 | | 20.02.2025 | Shamrock Rovers - Molde 0-1 Efs |
| 57. | 0-1 | Michael Noonan | | 10. | 0-1 | Magnus Eikrem |
| | | | | 90+3. |  | Isak Amundsen, Molde |
|
|   Borac Banja Luka til 1/8 finaler | |
| | 13.02.2025 | Borac Banja Luka - Olimpija Ljubljana 1-0 | | 20.02.2025 | Olimpija Ljubljana - Borac Banja Luka 0-0 |
| 52. |  | Raul Florucz, Olimpija Ljubljana | | | | |
| 90+1. | 1-0 | Sandi Ogrinec | | | |
|
|   Real Betis til 1/8 finaler | |
| | 13.02.2025 | Gent - Real Betis 0-3 | | 20.02.2025 | Real Betis - Gent 0-1 |
| 47. | 0-1 | Antony | | 82. | | Vitor Roque, Real Betis |
| 72. | 0-2 | Cedric Bakambu | | 87. | 0-1 | Archie Brown |
| 84. | 0-3 | Sergi Altimira | | | |
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|   Jagiellonia Bialystok til 1/8 finaler | |
| | 13.02.2025 | TSC - Jagiellonia Bialystok 1-3 | | 20.02.2025 | Jagiellonia Bialystok - TSC 3-1 |
| 28. | 1-0 | Vieljeux Mboungou | | 8. | 1-0 | Kristoffer Hansen |
| 31. | 1-1 | Jesus Imaz | | 17. | 1-1 | Marko Lazetic |
| 81. | 1-2 | Afimico Pululu | | 70. | 2-1 | Jesus Imaz |
| 89. | 1-3 | Jesus Imaz | | 76. | 3-1 | Selvmål, Viktor Radojevic |
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| Celje til 1/8 finaler | |
| | 13.02.2025 | Celje - APOEL 2-2 | | 20.02.2025 | APOEL - NK Celje 0-2 |
| 2. | 1-0 | Armandas Kucys | | 45+4. | 0-1 | Armandas Kucys |
| 32. | 1-1 | David Abagna | | 51. | 0-2 | Tamar Svetlin |
| 59. | 2-1 | Armandas Kucys | | | |
| 70. | 2-2 | Konstantinos Laifis | | | | |
| 73. | | Lasha Dvali, APOEL | | | | |
|
|   Panathinaikos til 1/8 finaler | |
| | 13.02.2025 | Vikingur Reykjavik - Panathinaikos 2-1 | | 20.02.2025 | Panathinaikos - Vikingur Reykjavik 2-0 |
| 13. | 1-0 | David Atlason | | 70. | 1-0 | Filip Mladenovic |
| 56. | 2-0 | Matthias Vilhjalmsson | | 90+5. | 2-0 | Tete |
| 90+1. | 2-1 | Fotis Ioannidis, straffe | | | |
|
|   FC København til 1/8 finaler | |
| | 13.02.2025 | FC København - Heidenheim 1-2 | | 20.02.2025 | Heidenheim - FC København 1-3 Efs |
| 45+1. | 1-0 | Jordan Larsson | | 37. | 0-1 | Amin Chiakha |
| 59. | 1-1 | Thomas Keller | | 53. | 0-2 | Kevin Diks, straffe |
| 85. | 1-2 | Tim Siersleben | | 73. | 1-2 | Leo Scienza |
| | | | | 114. | 1-3 | Rodrifo Huescas |
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